EVANS, Ronald M.,DOWNES, Michael,SHERMAN, Mara,DING, Ning
申请号:
EP15747042
公开号:
EP3104845A4
申请日:
2015.02.10
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present disclosure provides compositions that include a nanoparticle and a compound that reduces the biological activity of one or more bromodomain and extra-terminal family member (BET) proteins (e.g., a bromodomain inhibitor), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell.