您的位置: 首页 > 农业专利 > 详情页

GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS OF USE THEREOF
专利权人:
Regeneron Pharmaceuticals, Inc. ;Yale University ;Institute for Research in Biomedicine (IRB)
发明人:
Herndler-Brandstetter Dietmar,Flavell Richard A.,Frleta Davor,Gurer Cagan,Manz Markus Gabriel,Murphy Andrew J.,Palm Noah W.,Shan Liang,Stevens Sean,Strowig Till,Yancopoulos George D.,de Zoete Marcel
申请号:
US201815954450
公开号:
US2018295820(A1)
申请日:
2018.04.16
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
Genetically modified non-human animals expressing human SIRPα and human IL-15 from the non-human animal genome are provided. Also provided are methods for making non-human animals expressing human SIRPα and human IL-15 from the non-human animal genome, and methods for using non-human animals expressing human SIRPα and human IL-15 from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human T cell and/or natural killer (NK) cell development and function, in modeling human pathogen infection of human T cells and/or NK cells, and in various in vivo screens.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充