Aryl- {4-halogen-4 - [(heteroaryl-methylamino) -methyl] -piperidin-1-yl} -methane derivative and its use in the manufacture of medicaments

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专利权人:

PIERRE FABRE MEDICAMENT

发明人:

BERNARD VACHER,BERNARD BONNAUD,JEAN-LOUIS MAUREL,FRANCIS COLPAERT

申请号：

BR0311976

公开号：

BRPI0311976B1

申请日:

2003.06.18

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

1-Benzoyl-4-(N-(heteroarylmethyl)-aminomethyl)-piperidine derivatives (I) are new. Piperidine derivatives of formula (I) and their tautomers and optionally hydrated addition salts with mineral or organic acids are new. X, Y = CH or N； A = Me, CH2F, CN, OH, OMe, Cl or F； G = Cl or F； D = H, Cl, F, CN or CF3； and E = H, F or Cl； Provided that if A = Me and X = Y = CH, then G is Cl.

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