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Pochodna pirydoindolonu, sposób jej wytwarzania, srodek farmaceutyczny zawierajacy te pochodna oraz zastosowanie tej pochodnej
- 专利权人:
- SANOFI-AVENTIS
- 发明人:
- BOURRIE BERNARD,BERNARD BOURRIE,CASELLAS PIERRE,PIERRE CASELLAS,CIAPETTI PAOLA,PAOLA CIAPETTI,DEROCQ JEAN-MARIE,JEAN-MARIE DEROCQ,JEGHAM SAMIR,SAMIR JEGHAM,MUNEAUX YVETTE,YVETTE MUNEAUX,WERMUTH CAMILL,CAMILLE-GEORGE
- 申请号：
- PL376790
- 公开号：
- PL214867B1
- 申请日:
- 2003.10.21
- 申请国别(地区):
- PL
- 年份:
- 2013
- 代理人:
- 摘要：
- 3-Phenyl pyridoindolone derivatives (I) are new. 3-Phenyl pyridoindolone derivatives (I), their acid addition salts, hydrates and solvates are new. R1 = H, 1-4C alkyl, -(CH2)nCOO-(1-4C alkyl), or -(CH2)nCOONR6R7； R2 = H or 1-4C alkyl； R3 = phenyl (monosubstituted by OH, HO-CH2, COOH, 1-4C alkoxy carbonyl, hydroxyiminomethyl, 1-4C alkyl sulfonyl, CF3, SH, 1-4C alkylthio, CN, (CH2)mNR6R7, or CONR6R8), phenyl (substituted 2-5 times by halogen, 1-4C alkyl, CF3, OH, HOCH2, SH, 1-4C alkylthio, 1-4C alkyl sulfonyl, CN, (CH2)mNR6R7, or CONR6R8), or benzodioxolyl； R4, R5 = H, halogen, OH, 1-4C alkyl or alkoxy, CF3, 1-4C alkoxy carbonyl, CN or O-(CH2)nR6R7； R6 = H or 1-4C alkyl； R7 = H or 1-4C alkyl； or NR6R7 = piperidyl, morpholinyl, pyrrolidinyl, piperazinyl, or 4-methyl piperazin-1-yl； R8 = H, 1-4C alkyl, or -(CH2)n-NR6R7； or NR6R8 = piperidyl, morpholinyl, pyrrolidinyl, piperazinyl, or 4-methylpiperazin-1-yl； n = 1-3； and m = 0 or 1；
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
