Hans Lönn;Asim Ray;Marianne Ivarsson;Karolina Lawitz;Peter Hansen;Antonios Nikitidis
发明人:
Peter Hansen,Marianne Ivarsson,Karolina Lawitz,Hans Lönn,Antonios Nikitidis,Asim Ray
申请号:
US12299878
公开号:
US08114881B2
申请日:
2007.05.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides compounds of formulawherein R1, R3, R4, R5, R14, X and W are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of human neutrophil elastase.