2-pyridone derivatives for the treatment of diseases or conditions where inhibition of neutrophil elastase activity is beneficial

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专利权人:

アストラゼネカ・アクチエボラーグ

发明人:

ペーター・ハンセン,マリアンネ・イヴァーション,カロリナ・ラヴィッツ,ハンス・レン,アントニオス・ニキティディス,アシム・レイ

申请号：

JP2009509486

公开号：

JP5527739B2

申请日:

2007.05.07

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The invention provides compounds of formula wherein R1, R3, R4, R5, R14, X and W are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof； together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of human neutrophil elastase.

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