CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
发明人:
ERITJA CASADELLA, RAMON,OCAMPO, SANDRA MILENA,BLASCO SOLE, FRANCESC XAVIER,PERALES LOSA, JOSE CARLOS
申请号：
EP11774452
公开号：
EP2565278A4
申请日:
2011.04.26
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention relates to a method for obtaining formulations which improve the binding capacity of siRNAs in relation to plasma components, which promote the transport of siRNA in the blood, which increase the passage of siRNA through the cell membrane and, consequently, which increase the inhibitory activity of siRNA. The invention also relates to a method for obtaining a formulation comprising siRNA associated with plasma components, characterised in that the method includes a step in which the plasma components are dispersed in an aqueous medium.
