CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
发明人:
Ramon ERITJA CASADELLA,Sandra Milena OCAMPO,Francesc Xavier BLASCO SOLE,Jose Carlos PERALES LOSA
申请号：
US13661081
公开号：
US20130108686A1
申请日:
2012.10.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to a method for obtaining formulations which improve the binding capacity of siRNAs in relation to plasma components, which promote the transport of siRNA in the blood, which increase the passage of siRNA through the cell membrane and, consequently, which increase the inhibitory activity of siRNA. The invention also relates to a method for obtaining a formulation comprising siRNA associated with plasma components, characterised in that the method includes a step in which the plasma components are dispersed in an aqueous medium.
