THE UNITED STATES OF AMERICA AS REPRESENTED BY THE
发明人:
DHARMASENA, MADUSHINI NIROSHA,KOPECKO, DENNIS J.
申请号:
HK15112845.5
公开号:
HK1211980A
申请日:
2015.12.30
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
A recombineered Salmonella typhi Ty21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.