THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES;GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTD BY THE SECRETARY OF THE DEPARTMENT OF HEAL
发明人:
申请号：
IL23733915
公开号：
IL237339A
申请日:
2015.02.22
申请国别(地区):
IL
年份:
2019
代理人:
摘要：
A recombineered Salmonella typhi Ty21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.
