THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH & HUMAN SERVICES
发明人:
DHARMASENA, MADUSHINI NIROSHA,KOPECKO, DENNIS J.
申请号：
EP13836396
公开号：
EP2895596A4
申请日:
2013.09.16
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
A recombineered Salmonella typhi Ty21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.
