THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
Adi Barzel,Mark A. Kay
申请号：
US15126860
公开号：
US20170088856A1
申请日:
2015.03.19
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods and compositions are provided for editing the genome of a cell without the use of an exogenously supplied nuclease. Aspects of the methods include contacting a cell with a targeting vector comprising nucleic acid sequence to be integrated into the target locus, where the cell is not also contacted with a nuclease. In addition, reagents, devices and kits thereof that find use in practicing the subject methods are provided.
