The Board of Trustees of the Leland Stanford Junior University
发明人:
BARZEL, Adi,KAY, Mark A.
申请号：
EP15764889
公开号：
EP3119895A4
申请日:
2015.03.19
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Methods and compositions are provided for editing the genome of a cell without the use of an exogenously supplied nuclease. Aspects of the methods include contacting a cell with a targeting vector comprising nucleic acid sequence to be integrated into the target locus, where the cell is not also contacted with a nuclease. In addition, reagents, devices and kits thereof that find use in practicing the subject methods are provided.
