METHODS FOR DRUG DELIVERY COMPRISING UNFOLDING AND FOLDING PROTEINS AND PEPTIDE NANOPARTICLES

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专利权人:

NANJING UNIVERSITY

发明人:

HU, YIQIAO,WU, JINHUI,DING, DAWEI,GONG, GUANGMING,TANG, XIAOLEI,TONG, CHUNHUI,ZHU, YAN,LI, SHAOLING

申请号：

EP10808554

公开号：

EP2464224A4

申请日:

2010.08.06

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/