Miguel de los Rios,Kenneth J. Oh,Timothy L. Bullock,Patrick T. Johnson,Jacek Ostrowski
申请号：
US13353222
公开号：
US20140010885A1
申请日:
2012.01.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A self-assembling nanoparticle drug delivery system for the delivery of various bioactive agents including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as Hepatitis B Virus core protein, encapsulating the bioactive agent, a lipid layer or lipid/cholesterol layer coat and targeting or facilitating molecules anchored in the lipid layer. A method for construction of the self-assembling nanoparticle drug delivery system is also provided.
