Yiqiao Hu,Jinhui Wu,Dawei Ding,Guangming Gong,Xiaolei Tang,Chunhui Tong,Yan Zhu,Shaoling Li
申请号:
US12851600
公开号:
US09066870B2
申请日:
2010.08.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.