CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人:
MIGNET, NATHALIE,BOUDY, VINCENT PIERRE-MARIE,SEGUIN, JOHANNE,SCHERMAN, DANIEL,BELDENGRUN, YORAN
申请号：
CA2998541
公开号：
CA2998541A1
申请日:
2016.09.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to gelling compositions, which changes from liquid state to gel state in function of temperature comprising: at least a poloxamer or mixture of poloxamers at least a gelling agent and at least an anticancer agent. Said compositions are advantageously used for local administration of an anticancer agent. Said compositions are useful for size-reduction of a tumour before surgical removal of said tumour, for preventing tumour recurrence after surgical removal of a tumour, and/or treating small tumours. They are therefore useful for the treatment of cancer, preferably a cancer of a wall of the digestive system or a gynaecologic cancer. The present invention also relates to a method for preparing said gelling compositions.
