Institut National de la Sante et de;Centre National de la Recherche Scientifique (CNRS);Universite Paris Descartes;Assistance Publique - Hopitaux de Paris;Ecole Nationale Superieure de Chimie de Paris
发明人:
Mignet, Nathalie,Boudy, Vincent Pierre-Marie,Seguin, Johanne,Scherman, Daniel,Beldengrun, Yoran
申请号：
AU2016323727
公开号：
AU2016323727A1
申请日:
2016.09.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to gelling compositions, which changes from liquid state to gel state in function of temperature comprising: at least a poloxamer or mixture of poloxamers； at least a gelling agent； and at least an anticancer agent. Said compositions are advantageously used for local administration of an anticancer agent. Said compositions are useful for size-reduction of a tumour before surgical removal of said tumour, for preventing tumour recurrence after surgical removal of a tumour, and/or treating small tumours. They are therefore useful for the treatment of cancer, preferably a cancer of a wall of the digestive system or a gynaecologic cancer. The present invention also relates to a method for preparing said gelling compositions.
