The present invention relates to cementitious compositions, the cementitious compositions become gel state from liquid according to temperature, and the cementitious compositions include: the mixture of at least one poloxamer or poloxamer At least one gelling agent And at least one anticancer agent. The composition is advantageously used in local application anticancer agent. The composition is used for before operation cuts off the tumour, reduces the size of tumour, for preventing tumor recurrence and/or treatment little tumour after ocal resection. Therefore, treating cancer, the preferably cancer or gynecological cancer of digestive system wall are used for. The invention further relates to the methods for being used to prepare the cementitious compositions.