DISRUPTION CIBLEE D'UN GENE MEMBRE DE LA VOIE CSF1-DAP12 POUR LE TRAITEMENT DE LA DOULEUR NEUROPATHIQUE

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专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

BASBAUM, ALLAN,KUHN, JULIA,GUAN, ZHONGHUI

申请号：

CA2963940

公开号：

CA2963940A1

申请日:

2015.10.08

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The invention provides compositions and methods for treating neuropathic pain. Specifically, the disclosure provides a polynucleotide comprising a trigeminal ganglion (TGG) or dorsal root ganglion (DRG) promoter operably linked to a recombinant nucleic acid encoding an endonuclease that binds to a nucleotide sequence in the human colony stimulating factor 1 (hCSF1 ) gene and a method of using the polynucleotide or a vector comprising the polynucleotide for treatment of neuropathic pain.

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中国工程科技知识中心

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http://www.ckcest.cn/home/