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TARGETED DISRUPTION OF A CSF1-DAP12 PATHWAY MEMBER GENE FOR THE TREATMENT OF NEUROPATHIC PAIN
专利权人:
The Regents of the University of California
发明人:
Allan Basbaum,Julia Kuhn,Zhonghui Guan
申请号:
US15516872
公开号:
US20170354745A1
申请日:
2015.10.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides compositions and methods for treating neuropathic pain. Specifically, the disclosure provides a polynucleotide comprising a trigeminal ganglion (TGG) or dorsal root ganglion (DRG) promoter operably linked to a recombinant nucleic acid encoding an endonuclease that binds to a nucleotide sequence in the human colony stimulating factor 1 (hCSF1) gene and a method of using the polynucleotide or a vector comprising the polynucleotide for treatment of neuropathic pain.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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