A signal calibration method and system for a detector for X-ray detection are disclosed. According to an embodiment of the present invention, there is provided a signal calibration method for a detector for X-ray detection using a detector signal calibration system 10 including a detector inspection apparatus 100 and an X-ray imaging apparatus 200, The X-ray imaging apparatus 200 includes a first X-ray irradiator 110 and a first microprocessor 120. The X-ray radiographing apparatus 200 includes a second X-ray irradiator 210, a calibration target detector D, Wherein the calibration method comprises the steps of: (S10) acquiring a plurality of dark images for the detector (D) by the first microprocessor (120) and for each pixel of the detector (D) Calculating a deviation and a primary offset; (S20) selecting the first group bad pixel (BP1) based on the signal standard deviation and the first offset information by the first microprocessor (120); (S30) obtaining a plurality of bright images with respect to the detector (D) by the first microprocessor (120) to calculate a second offset and a gain for each pixel of the detector (D); (S40) selecting the second group bad pixel (BP2) based on the second offset and the gain information by the first microprocessor (120); (S50) The first microprocessor (120) corrects the detection signal of each pixel obtained at the time of acquiring the bright image based on the calibration signal value corrected based on the primary offset, the secondary offset and the gain Completing a bad pixel map (BPM) by selecting three group bad pixels (BP3); And (S60) correcting the signals of the bad pixels using the bad pixel map (BPM) by the second microprocessor 220 when the X-ray image of the subject is taken with the X-A detector for detecting an X-ray beam, the method comprising the steps of:X선 검출용 디텍터의 신호 교정 방법 및 시스템이 개시된다. 일 실시예에 따르면, 디텍터 검사 장비(100)와 X선 촬영 장비(200)로 구성된 디텍터 신호 교정 시스템(10)을 이용한 X선 검출용 디텍터의 신호 교정 방법으로서, 상기 디텍터 검사 장비(100)는 제1 X선 조