Dietrich Wilhelm Schacht,Mike Hannay,Hans-Michael Wolff
申请号：
US10623864
公开号：
US08246979B2
申请日:
2003.07.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An improved transdermal delivery system (TDS) comprises a self-adhesive matrix comprising a solid or semi-solid semi-permeable polymer which contains rotigotine in its free base form as a multitude of microreservoirs within the matrix. The self-adhesive matrix is highly permeable to the free base of rotigotine and is impermeable to the protonated form of rotigotine.
