Dietrich Wilhelm Schacht,Mike Hannay,Hans-Michael Wolff
申请号：
US10627990
公开号：
US08246980B2
申请日:
2003.07.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An improved transdermal delivery system (TDS) comprises a self-adhesive matrix comprising a solid or semi-solid semi-permeable polymer which contains an amine-functional drug in its free base form as a multitude of microreservoirs within the matrix. The self-adhesive matrix is highly permeable to the free base of the amine-functional drug and is impermeable to the protonated form of the amine-functional drug.
