您的位置: 首页 > 农业专利 > 详情页

MUTANT VESICULAR STOMATITIS VIRUSES AND USE THEREOF
专利权人:
OTTAWA HEALTH RESEARCH INSTITUTE
发明人:
BELL, JOHN C.,LICHTY, BRIAN D.,STOJDL, DAVID F.
申请号:
CA2520279
公开号:
CA2520279C
申请日:
2004.03.29
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides mutant viruses with a decreased ability toblock nuclear transport of mRNA or protein in an infected cell which areattenuated in vivo. The mutant viruses of the present invention may also becapable of triggering the anti-viral systems of normal host cells whileremaining sensitive to the effects of these systems. The present inventionfurther provides for the use of the mutant viruses in a range of applicationsincluding, but not limited to, as therapeutics for the treatment of cancer andinfections, as vaccines and adjuvants, as viral vectors, and as oncolytic andcytolytic agents for the selective lysis of malignant or infected cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充