A composition for reducing weight and lowering lipid, a preparation method therefor, and a use thereof. The pharmaceutical composition comprises the following crude drugs: 18-65 parts by weight of phloridzin or pharmaceutically acceptable salts thereof; and 15-78 parts by weight of a turmeric extract. The pharmaceutical composition has the effects of weight reducing and lipid lowering, and the pharmaceutical composition has better effects of weight reducing and lipid lowering than a single crude drug.