Breitbart, Eyal,Leubitz, Andrea,Feige, Erez,Penson, Richard
申请号:
AU2017202492
公开号:
AU2017202492B2
申请日:
2017.04.18
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2017202492B220180906.pdf#####ABSTRACT The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor or inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient by administering an adenovirus comprising a nucleic acid construct comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter. Also provided is a homogeneous population of an adenovirus comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter and its uses thereof.