BREITBART, Eyal,LEUBITZ, Andrea,FEIGE, Erez,PENSON, Richard
申请号:
AU2018271398
公开号:
AU2018271398A1
申请日:
2018.11.30
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018271398A120181220.pdf#####ABSTRACT The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor or inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient by administering an adenovirus comprising a nucleic acid construct comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter. Also provided is a homogeneous population of an adenovirus comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter and its uses thereof.