BREITBART, EYAL,LEUBITZ, ANDREA,FEIGE, EREZ,PENSON, RICHARD
申请号:
PL13847711
公开号:
PL2908865T3
申请日:
2013.10.17
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor or inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient by administering an adenovirus comprising a nucleic acid construct comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter. Also provided is a homogeneous population of an adenovirus comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter and its uses thereof.