Philipp Hadwiger,Torsten Hoffmann,Kerstin Jahn-Hofmann,Eric A. Kitas,David L. Lewis,Peter Mohr,Hans Martin Mueller,Guenther Ott,Ingo Roehl,David B. Rozema
申请号：
US13917524
公开号：
US20140135381A1
申请日:
2013.06.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.
