Philipp Hadwiger,Torsten Hoffmann,Kerstin Jahn-Hofmann,Eric A. Kitas,David L. Lewis,Peter Mohr,Hans Martin Mueller,Guenther Ott,Ingo Roehl,David B. Rozema
申请号：
US15090147
公开号：
US09968647B2
申请日:
2016.04.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.
