A compound of formula (II), or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein: R1, R2, R9, R10, R11 R12, R13 and R14 are independently selected from hydrogen, halogen, cyano, nitro, azido , -OR3, -NR4C (O) OR6, -OC (O) R3, -NR4S (O) jR6, -S (O) jNR3R4, -S (O) jNR4C (O) R3, -C (O) NR4S ( O) jR6, S (O) jR6, -NR4C (O) R3, -C (O) NR3R4, -NR5C (O) NR3R4, -NR5C (NCN) NR3R4, -NR3R4 and C1-C10 alkyl, C2-C10 alkenyl , C2-C10alkynyl, C3-C10 cycloalkyl, C3-C10 cycloalkylalkyl, -S (O) j (C1-C6 alkyl), where each alkyl, alkenyl, alkynyl and cycloalkyl, is substituted or unsubstituted with 1 to 5 substitutes selected from the group consisting of primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro, or trihalomethyl. R3 is selected from hydrogen, trifluoromethyl, C1-C10 alkyl, C2-10 alkenyl, C2-C10 alkynyl, C3-C10 cycloalkyl, and C3-C10 cycloalkylalkyl, where each alkyl, alkenyl, alkynyl and cycloalkyl is substituted or unsubstituted with from 1 to 5 constituents selected from the group consisting of primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro, or trihalomethyl； R4 is selected from hydrogen or C1-C6 alkyl, where the alkyl may be substituted or unsubstituted with from 1 to 5 substituents selected from the group consisting of primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro, or trihalomethyl. R5 is sealed from hydrogen or C1-C6 alkyl, where the alkyl may be substituted or unsubstituted with from 1 to 5 substituents selected from the group consisting of primary amino, aminocarbonyl, carboxyl, cyano, halogen, hydroxy, nitro, or trihalomethyl. R6 is sealed from trifluoromethyl； and C1-C10 alkyl, C3-C10 cycloalkyl, R ', R' 'are independently sealed from hydrogen, C1-C4 alkyl, C2-C4 alkenyl, aryl and arylalkyl； W is -C (O) OR15, C (O) NR4R15, -C (O) NR4OR15, C (O) NR4S (O) jR6, -C (O) NR4NR4R15, -NR'S (O) jR ', -NRC ( O) NR'R ", NR'S (O) jNR'R", or -C (O) NR4NR4C (O) R15； Provided that W is not C
