WINTERS, GEOFFREY C.,MANDEL, ALEXANDER LAURENCE,RICH, JAMES R.,HEDBERG, BRADLEY JOHN,HSIEH, TOM HAN HSIAO,BOURQUE, ELYSE MARIE JOSÉE,BABCOOK, JOHN
申请号：
EP14763699
公开号：
EP2968440A4
申请日:
2014.03.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
