BOURQUE, ELYSE MARIE JOSEE,BABCOOK, JOHN,HEDBERG, BRADLEY JOHN,HSIEH, TOM HAN HSIAO,MANDEL, ALEXANDER LAURENCE,RICH, JAMES R.,WINTERS, GEOFFREY C.
申请号：
CA2906784
公开号：
CA2906784A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
