12345610111 1222337891 1222331 4The present disclosure provides an antimicrobial composition including a polycationic amphiphile compound and the method of making and the method of using such a compound or composition. The compound having the formula (I) or (II) R R R R R R R or R is H or a C alkyl unsubstituted or optionally substituted with a functional group such as OH OR NH NHR NR N C(0)R N C(0)CR =CR SH SR 0 C(0)R C(0)R CF OCF halogen benzyl o vinylbenzyl m vinylbenzyl p vinylbenzyl phenyl allyl and substituted allyl. R R or R is a C alkyl unsubstituted or optionally substituted with a functional group such as OH OR NH NHR NR SH SR 0 C(0)R C(0)R CF and OCF. R is H or a C alkyl. X or Y is a halogen m and n are integers in the range from 1 to 25.
