PROBLEM TO BE SOLVED: To provide methods for producing HMBCa (β-hydroxy-β-methylbutyrate calcium)-containing granules that are easy to dissolve in water and also suitable for packaging in sachet.SOLUTION: The HMBCa containing granules of the present invention are produced by a stirring and granulation step of stirring and granulating with a binding solution a raw material containing HMBCa powders and dextrin powders, a particle-sizing step of sizing granules obtained by the stirring and granulation step into a particulate material with a predetermined diameter or less, and a fluid layer granulation step of granulating a row material comprising the particulate material by fluidized bed granulation method to obtain MHBCa-containing granules.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】水に溶かしやすく、小分け包装にも適したＨＭＢＣａ（β-ヒドロキシ-β-メチル酪酸カルシウム）含有顆粒の製造方法を提供する。【解決手段】ＨＭＢＣａの粉末とデキストリンの粉末とを含む原料を、結合液とともに攪拌して造粒する攪拌・造粒工程と、攪拌・造粒工程で得られた造粒物を、所定粒径以下の粉粒体に整粒する整粒工程と、前記粉粒体を含む原料を流動層造粒法によって造粒して、ＨＭＢＣａを含有する顆粒を得る流動層造粒工程とによってＨＭＢＣａ含有顆粒を製造する。【選択図】なし
