Lawrence M. Kauvar,Stote Ellsworth,William Usinger,Krista Maureen McCutcheon,Ying-Ping Jiang,Fen Zhang,Bo Chen,Gizette Sperinde,Minha Park,Orit Foord
申请号：
US15464165
公开号：
US10030069B2
申请日:
2017.03.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Recombinant monoclonal antibodies to human cytomegalovirus (CMV) gB protein are described. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, the invention antibodies are useful as therapeutic and prophylactic agents to prevent or ameliorate effects on the fetus of CMV infection during pregnancy.
