LAWRENCE M. KAUVAR,STOTE ELLSWORTH,WILLIAM USINGER,KRISTA MAUREEN MCCUTCHEON,YING-PING JIANG,FEN ZHANG,BO CHEN,GIZETTE SPERINDE,MINHA PARK,ORIT FOORD
申请号：
US13162497
公开号：
US20120020980A1
申请日:
2011.06.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Antibodies to human Cytomegalovirus (CMV) gB protein have been isolated from human B cells. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, the invention antibodies are useful as therapeutic and prophylactic agents to prevent or ameliorate effects on the fetus of CMV infection during pregnancy.
