Kauvar, Lawrence M.,Ellsworth, Stote,Usinger, William,McCutcheon, Krista Maureen,Jiang, Ying-Ping,Zhang, Fen,Chen, Bo,Sperinde, Gizette,Park, Minha,Foord, Orit
申请号：
AU2011268277
公开号：
AU2011268277B2
申请日:
2011.06.16
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Antibodies to human Cytomegalovirus (CMV) gB protein have been isolated from human B cells. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, the invention antibodies are useful as therapeutic and prophylactic agents to prevent or ameliorate effects on the fetus of CMV infection during pregnancy.
