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Creamy composition of oil-in-water emulsion and its production process
专利权人:
Otsuka Pharmaceutical Co.; Ltd.
发明人:
WAKAMATSU, Kosaburo
申请号:
ES09758326
公开号:
ES2567044T3
申请日:
2009.06.02
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A creamy oil-in-water emulsion composition containing the following Components (A) to (F) and (H) in the following proportions based on their total amount, in which the viscosity of the emulsion composition at 20 ° C is 5000 to 60,000 cps: (A) not less than 0.1% by weight of adenosine phosphate ester selected from at least one member selected from the group consisting of 3 ', 5'-cyclic adenosine monophosphate, adenosine monophosphate, adenosine monophosphate adenosine, adenosine triphosphate, and salts thereof; (B) 0.5 to 6% by weight of fatty acid ester with polyglycerin; (C) 0.05 to 0.7% by weight of acrylic acid alkyl methacrylate copolymer; (D) 0.5 to 10% by weight of amphiphilic lipid, comprising at least one member selected from the group consisting of C14-22 fatty acids, C8-22 alcohols, C8-22 monoalkyl glyceryl ethers, ceramides, saccharides of ceramides, sugar lipids, lecithins and lecithin derivatives; (E) 0.5 to 20% by weight of polyhydroxylated alcohol; (F) 0.3 to 5% by weight of self-emulsifying fatty acid monoester with glycerin; and (H) 10 to 30% by weight of oil.Una composición cremosa de emulsión de aceite en agua que contiene los siguientes Componentes (A) a (F) y (H) en las siguientes proporciones basadas en su cantidad total, en la que la viscosidad de la composición de emulsión a 20ºC es 5000 a 60000 cps: (A) no menos de 0,1% en peso de éster de fosfato de adenosina seleccionado de al menos un miembro seleccionado del grupo que consiste en 3',5'-monofosfato de adenosina cíclico, monofosfato de adenosina, difosfato de adenosina, trifosfato de adenosina, y sales de los mismos; (B) 0,5 a 6% en peso de éster de ácido graso con poliglicerina; (C) 0,05 a 0,7% en peso de copolímero de ácido acrílico-metacrilato de alquilo; (D) 0,5 a 10% en peso de lípido anfifílico, que comprende al menos un miembro seleccionado del grupo que consiste en ácidos grasos de C14-22, alcoholes de C8-22, monoalquil C8-22 gliceril éteres, ceramidas, sacáridos de ceramidas, líp
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