The invention relates to polypeptides exhibiting metabolic-modulating as well as immunomodulatory properties, nucleic acids encoding them, compositions comprising them, and methods of treating metabolic disorders and/or immune-related disorders comprising their administration and to their use in preparing pharmaceutical compositions for the treatment, amelioration, prophylaxis or delaying the onset of at least one of a metabolic disorder and an immune-related disorder.本発明は、代謝調節並びに免疫調節特性を示すポリペプチド、それらをコードする核酸、それらを含む組成物、それらの投与を含む、代謝障害及び／又は免疫関連障害を治療するための方法、代謝障害及び免疫関連障害の少なくとも１つの治療、改善、予防又はその発症の遅延のための医薬組成物を調製する際のそれらの使用に関する。
