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Heterocyclic Acetic Acid Amide Compound
专利权人:
Astellas Pharma Inc.
发明人:
SHIRAKI, Ryota,TOBE, Takahiko,KAWAKAMI, Shimpei,MORITOMO, Hiroyuki,OHMIYA, Makoto
申请号:
DK14786115
公开号:
DK2987793T3
申请日:
2014.04.18
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
[Problem] A compound which is useful as a dopamine D1 receptor positive allosteric modulator (D1 PAM) is provided. [Means for Solution] The present inventors have studied a compound which has a dopamine D1 receptor positive allosteric modulating activity and is useful as an active ingredient of a pharmaceutical composition for preventing and/or treating cognitive impairment, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug addictions, or the like, and they have thus found that a heterocyclic acetamide compound has a dopamine D1 receptor positive allosteric modulating activity, thereby completing the present invention. The heterocyclic acetamide compound of the present invention has a dopamine D1 receptor positive allosteric modulating activity and can be used as an agent for preventing and/or treating cognitive impairment, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug addictions, or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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