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Heterocyclic acetic acid amide compounds
专利权人:
アステラス製薬株式会社
发明人:
白木 良太,戸部 貴彦,川上 晋平,森友 博幸,大宮 誠
申请号:
JP2015512531
公开号:
JP6252582B2
申请日:
2014.04.18
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
[Problem] A compound which is useful as a dopamine D1 receptor positive allosteric modulator (D1 PAM) is provided. [Means for Solution] The present inventors have studied a compound which has a dopamine D1 receptor positive allosteric modulating activity and is useful as an active ingredient of a pharmaceutical composition for preventing and/or treating cognitive impairment, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug addictions, or the like, and they have thus found that a heterocyclic acetamide compound has a dopamine D1 receptor positive allosteric modulating activity, thereby completing the present invention. The heterocyclic acetamide compound of the present invention has a dopamine D1 receptor positive allosteric modulating activity and can be used as an agent for preventing and/or treating cognitive impairment, negative symptoms of schizophrenia, Parkinson's disease, Alzheimer's disease, Huntington's disease, drug addictions, or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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