MADISON, EDWIN L.,THANOS, CHRISTOPHER,BLOUSE, GRANT ELLSWORTH
申请号:
TW100139924
公开号:
TW201242975A
申请日:
2011.11.02
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Modified Factor IX (FIX) polypeptides and uses thereof are provided. Such modified FIX polypeptides include FIXa and other forms of FIX. Among the modified FIX polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.