Edwin L. Madison;Grant Ellsworth Blouse;Christopher Thanos
发明人:
Edwin L. Madison,Christopher Thanos,Grant Ellsworth Blouse
申请号:
US14267754
公开号:
US09328339B2
申请日:
2014.05.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Modified Factor IX (FIX) polypeptides and uses thereof are provided. Such modified FIX polypeptides include FIXa and other forms of FIX. Among the modified FIX polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.