7. ABSTRACT Exemplary embodiments of the present disclosure are directed towards a method for the preparation of anti-cancer poly herbal formulation comprising of: weighing the roots of a herbal active ingredients from: Aegle marmelos, Mimosa pudica, Datura stramonium, Eclipta prostrata, Tribulus terrestris Linn, and Chrysopogon zizanioides, and each of the herbal active ingredient is subjected to washing and rinsing to be abraded against a sandalwood block, where the abraded herbal ingredients are subjected to intermediary sprinkling by additives like cow urine and water to obtain the poly herbal formulation.