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A mixture of biodegradable ingredients that regulates the release kinetics of at least one active ingredient
专利权人:
RECH, ANTHONY;MEDINCELL;ROBERGE, CHRISTOPHE;CROS, JEAN-MANUEL
发明人:
CROS, JEAN,MANUEL - RECH, ANTHONY,ROBERGE, CHRISTOPHE,SERINDOUX, JULIETTE,PETIT, AUDREY,PEBREL, LEA,LPEZ-NORIEGA, ADOLFO,ABBASSI, MYRIAM
申请号:
ARP180101987
公开号:
AR113096A1
申请日:
2018.07.17
申请国别(地区):
AR
年份:
2020
代理人:
摘要:
1. There are biodegradable components in drug management, including: (1) a mixture composed of at least three copolymers of different blocks, each of which is: (a) a biodegradable copolymer, whose formula is a7515-b695a-739a is polyester, B is polyethylene, V and X are polyethylene; a. 1 to 3000 to W is 3 to 300 to v = x or v 1 x; or (b) a biodegradable capsule copolymer, the formula of which is: c696-a7611a is polyester, C is polyethylene of protected extreme, e and Z are repetition units, y = 2 to 250 and z = 1 to 3000;2. The mixture contains at least one (a) and one (b);The weight ratio between (a) and (b) is 1:19 to 5:1; for at least one co Olympic member calculated according to (a) or (b) a, this ratio is poly (lactate co ethanol) (PLGA);And (II) at least one effective pharmaceutical ingredient. 8. Claim 8: components that are biodegradable when a drug is used in accordance with any of the above requirements, The characteristics also include: (a) a biodegradable PVC, the formula is: PLGA 7515a-peg695a-plga739v, where V and X are the number of repeat units between 1 and 3000 to W, and between 3 and 300 to v = x or V = 1x;Y / O (b) a biodegradable copolymer coating: mpeg6966-plga7611a, where y and Z are the number of repeating units, ranging from 2 to 250 to Z and from 1 to 3000. 9. Claim 9: components that are biodegradable when a drug is used in accordance with any of the above requirements, 2. The composition also includes: and (a) a biodegradable polyvinyl chloride, the formula is: pcla7515-peg695a-pcla739v, where V and X are the number of repeat units between 1 to 3000 to W, and between 3 to 300 to v = x or V = 1x;Y / O (b) a biodegradable copolymer coating, the formula is: mpeg6966-pcla7611y, where y and Z are the number of repeating units, ranging from 2 to 250 to Z, ranging from 1 to 3000. 11. Claim 11: according to any one of the above requirements, the biodegradable component of the drug, which is characterized by that the component is an injectable liq
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