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A mixture of biodegradable ingredients that regulates the release kinetics of at least one active ingredient
专利权人:
RECH, ANTHONY;MEDINCELL;ROBERGE, CHRISTOPHE;CROS, JEAN-MANUEL
发明人:
SERINDOUX, JULIETTE,PETIT, AUDREY,PEBREL, LEA,LPEZ-NORIEGA, ADOLFO,ABBASSI, MYRIAM,RECH, ANTHONY,CROS, JEAN,MANUEL - ROBERGE, CHRISTOPHE
申请号:
ARP180101988
公开号:
AR113097A1
申请日:
2018.07.17
申请国别(地区):
AR
年份:
2020
代理人:
摘要:
The biodegradable components in drug management include: (1) a mixture of copolymers of at least three different blocks, a. The copolymers of each block are: (a) a biodegradable copolymer with formula: a7515a-b695a-a739a is polyester, B is polyethylene, V and X are 1 to 3000 to w repeat units, i.e. repeat units are 3 to 300 to v = x or V = x;O (b) a biodegradable copolymer, the formula of which is c6966-a7611a, wherein a is polyester, C is polyethylene of protected extreme, e and Z are the number of repeating units, in the range of 2 to 250 to Z, in the range of 1 to 3000; and the mixture includes at least 1 (a) and 1 (b);And the weight ratio between (a) and (b) is 1:19 to 5:1; and (II) at least one pharmaceutical active ingredient. 6. Claim 6: according to any one of the above requirements, a biodegradable component of the drug, characterized in that the component also includes: (a) a biodegradable copolymer with the formula: pla7515 Pegg 695-pla739v, wherein V and X are the number of repeating units; 3 to 300 to v = x or v 1 x in the range 1 to 3 000 to W;Y / O (b) a biodegradable copolymer coating, the formula is: mpeg6966-pl 7611y, where y and Z are the number of repeating units, ranging from 2 to 250 to Z, ranging from 1 to 3000. 7. Claim 7: a biodegradable component for the use of a drug according to any one of the requirements of items 1 to 6, which is characterized by: (a) a biodegradable copolymer with a formula: pla7515-peg695-pla739v, wherein V and X are the number of class 1 to class 1 repeat units; And 3000 and W are the number of repeating units in the range 3 to 300 to v = x or v 1 x; and (b) 2,Three or four different biodegradable diode copolymers, each of which has a formula: MPEG 696-pl 7611a, where y and Z are the number of repeating units, ranging from 2 to 250 to Z, ranging from 1 to 3000; the weight ratio (a) and (b) is 1:19 to 5:1. 8. Claim 8: any one of the drugs described in claims 1 to 7 uses biodegradable ingredients,The characteristics in
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