HUGHES, ADAM,FENSTER, ERIK,FLEURY, MELISSA,GENDRON, ROLAND,MORAN, EDMUND J.
申请号:
CA2850953
公开号:
CA2850953A1
申请日:
2012.11.01
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: (I) where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.