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INHIBITEURS DE NÉPRILYSINE
专利权人:
Theravance Biopharma R&D IP; LLC
发明人:
申请号:
EP12724047.1
公开号:
EP2714660B1
申请日:
2012.05.18
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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